Saturday, September 22, 2007

Oral Aloe Vera induced Hepatitis

A case of a 73-year-old female admitted to the hospital for acute hepatitis has been published in the Annals of Pharmacotherapy. Extensive laboratory testing did not reveal the cause of the patient's disease. She was asked multiple times whether she was taking any home medications, which she initially denied. It was only after an extensive medication history done by a clinical pharmacist that the patient admitted to using oral aloe vera capsules for constipation. Upon discontinuation of the oral aloe vera, liver markers of hepatotoxicity returned to normal levels.

Using the Roussel Uclaf Causality Assessment Method for determining drug hepatotoxicity, the patient's symptoms were scored as probably caused by oral aloe vera.

Source: The Annals of Pharmacotherapy 2007;41(10):1740-1743.

http://www.theannals.com/cgi/content/abstract/41/10/1740

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